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KMID : 0358420110540100634
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 10 p.634 ~ p.638
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A case of squamous cell carcinoma of the uterine cervix with diffuse hematogenous lung metastasis in a 36-year-old virgin
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Shim A-Ra
Choi Eun-Kyoung
Yun Sung-Hyun
Lee Maria
Lee Mi-Kyung
Kim Sang-Wun
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Abstract
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The carcinoma of the uterine cervix in virgins is extremely rare. A 36-year-old virgin presented with a 4.8 × 2.2 cm sized endocervical mass with bleeding on sonography. Biopsy revealed a squamous cell carcinoma arising in the uterine cervix without human papilloma virus (HPV) DNA. Positron emission tomography revealed cervical cancer with multiple hematogenous lung metastases. After 3 cycles of preoperative chemotherapy, she underwent modified radical hysterectomy and 6 cycles of postoperative chemotherapy. After the treatment, complete resolution was obtained, and she has been followed without recurrence for 4 years. Although > 90% of cervical cancer is caused by HPV infection, we cannot completely deny the possibility of HPV negative cervical carcinoma.
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KEYWORD
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Squamous cell carcinoma, Virgin, Human papilloma virus DNA negative
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